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Neurotherapeutics
Volume 4, Issue 1, Pages 1-172 (January 2007)
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New Antiepileptic Drugs: Discovery, Development, and Update
Edited by Roger J. Porter, Jacqueline A. French

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Editorials


It’s Official: NeuroRx is Now Neurotherapeutics free full text
Alan I. Faden
page 1
Full Text | Full-Text PDF (19 KB)


New Antiepileptic Drugs—Discovery, Development, and Update free full text
Roger J. Porter, Jacqueline A. French
pages 2-3
Full Text | Full-Text PDF (28 KB)

Part 1: The State of the State for Old and New AEDs: The Process


Currently Available Antiepileptic Drugs
Steven C. Schachter
pages 4-11
Abstract | Full Text | Full-Text PDF (107 KB)


Discovery of Antiepileptic Drugs
Misty Smith, Karen S. Wilcox, H. Steve White
pages 12-17
Abstract | Full Text | Full-Text PDF (82 KB)


Molecular Targets for Antiepileptic Drug Development free full text
Brian S. Meldrum, Michael A. Rogawski
pages 18-61
Abstract | Full Text | Full-Text PDF (6831 KB)


Clinical Development of Antiepileptic Drugs in Adults
Bernd Schmidt
pages 62-69
Abstract | Full Text | Full-Text PDF (84 KB)


Clinical Development of Antiepileptic Drugs for Children
Elizabeth Garofalo
pages 70-74
Abstract | Full Text | Full-Text PDF (74 KB)


Use of Antiepileptic Drugs for Nonepileptic Conditions: Psychiatric Disorders and Chronic Pain
Alan B. Ettinger, Charles E. Argoff
pages 75-83
Abstract | Full Text | Full-Text PDF (123 KB)

Part 2: Progress in Current AED Development: The Drugs

Drugs in Phase 1 and 2


Brivaracetam (UCB 34714)
Philipp von Rosenstiel
pages 84-87
Abstract | Full Text | Full-Text PDF (55 KB)


Eslicarbazepine Acetate (BIA 2-093)
Luis Almeida, Patrício Soares-da-Silva
pages 88-96
Abstract | Full Text | Full-Text PDF (587 KB)


Fluorofelbamate
Bryan A. Roecklein, Harry J. Sacks, Henry Mortko, James Stables
pages 97-101
Abstract | Full Text | Full-Text PDF (107 KB)


Ganaxolone
Virinder Nohria, Earl Giller
pages 102-105
Abstract | Full Text | Full-Text PDF (76 KB)


Carisbamate (RWJ-333369)
Gerald P. Novak, Michael Kelley, Peter Zannikos, Brian Klein
pages 106-109
Abstract | Full Text | Full-Text PDF (66 KB)


Safinamide
Ruggero G. Fariello
pages 110-116
Abstract | Full Text | Full-Text PDF (262 KB)


Seletracetam (UCB 44212)
Barbara Bennett, Alain Matagne, Philippe Michel, Michèle Leonard, Miranda Cornet, Marie-Anne Meeus, Nathalie Toublanc
pages 117-122
Abstract | Full Text | Full-Text PDF (241 KB)


Stiripentol
Catherine Chiron
pages 123-125
Abstract | Full Text | Full-Text PDF (53 KB)


Talampanel
John F. Howes, Cynthia Bell
pages 126-129
Abstract | Full Text | Full-Text PDF (63 KB)


Valproic Acid: Second Generation
Meir Bialer, Boris Yagen
pages 130-137
Abstract | Full Text | Full-Text PDF (171 KB)

Drugs in Phase 3


Clobazam
Yu-tze Ng, Stephen D. Collins
pages 138-144
Abstract | Full Text | Full-Text PDF (105 KB)


Lacosamide
Pamela Doty, G. David Rudd, Thomas Stoehr, Dirk Thomas
pages 145-148
Abstract | Full Text | Full-Text PDF (65 KB)


Retigabine
Roger J. Porter, Virinder Nohria, Chris Rundfeldt
pages 149-154
Abstract | Full Text | Full-Text PDF (102 KB)


Rufinamide
Santiago Arroyo
pages 155-162
Abstract | Full Text | Full-Text PDF (365 KB)


Vigabatrin
James W. Wheless, R. Eugene Ramsay, Stephen D. Collins
pages 163-172
Abstract | Full Text | Full-Text PDF (237 KB)

Frontmatter


Editorial Board
page A1
Full-Text PDF (21 KB)

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